San Francisco 49ers tight end George Kittle did not get the ball very much in his team's loss to the Buffalo Bills on Sunday ...

The Bills have clinched a playoff spot for the fifth straight year thanks to winning the AFC East for a fifth straight year.

The San Francisco 49ers on Tuesday announced how they’d replace running back Christian McCaffrey. In a slew of roster moves ...

The San Francisco 49ers have signed a former New York Jets running back to replace the injured Christian McCaffrey and Jordan ...

The San Francisco 49ers and fantasy football players who were relying on the NFC West team's running backs are probably all ...

Mia DeCamilla, an eight-year-old San Francisco 49ers fan and cancer survivor, was attending her first NFL game on Sunday ...

Just when it seemed that San Francisco 49ers running back Christian McCaffrey was starting to find his rhythm, in a moment of ...

The San Francisco 49ers could say goodbye to RB Jordan Mason, one of their most productive offensive players, in the near ...

The Buffalo Bills and San Francisco 49ers clashed in Week 13 contest to continue their respective 2024 NFL seasons. The Bills ...

The Buffalo Bills got after it against the San Francisco 49ers and ended up winning, 35-10, on Sunday during the NFL’s Week ...

The Buffalo Bills are making a kind gesture to the young fan who was pushed down the stairs during last Sunday night's game ...

Will the Bills pull off a perfect sweep of NFC West teams. There's a surprising mix of opinions on Buffalo's chances.