Pharmacogenomics. 2014;15(11):1507-1518. MEK/CDK4 PD-0325901 (MEKi) + palbociclib (CDK4i) NCT02022982 MEK/CDK4 Trametinib (MEKi) + palbociclib (CDK4i) NCT02065063 ...

Geode Capital Management LLC increased its position in Verastem, Inc. (NASDAQ:VSTM – Free Report) by 67.6% during the third ...

Verastem Oncology is not just another biotech company; it is making significant strides in treating cancers driven by RAS/MAPK signaling pathways. Its focus is on novel small molecule drugs that ...

Trametinib, a mitogen-activated protein kinase (MEK) inhibitor, reduces mortality and morbidity in children with severe ...

An NDA has been accepted by the FDA for the combination of avutometinib and defactinib in KRAS-mutated recurrent low-grade ...

Among the many metrics available, Relative Athletic Score (RAS) has emerged as a prominent tool in assessing a prospect’s athleticism. Developed by Kent Lee Platte, RAS has transformed how ...

Today will see largely cloudy skies with scattered showers, that will be wintry on the hills moving in from the north. Some brief brightness possible between the showers. Windy and cold. Tonight ...

33 ROW 1,3 BUTADIENE MARKET ESTIMATES AND FORECASTS, 2010 – 2018 (KILO TONS), (USD MILLION) FIG. 34 MEK MARKET VOLUME SHARES BY APPLICATIONS, 2011-2018 (KILO TONS) FIG. 35 PAINTS AND COATINGS AS AN ...

Variable cloud with a few showers this evening. Turning drier overnight with clear spells and a few patches of cloud, but a few light showers locally towards dawn and into the morning. A colder ...

Cataclysm:Dark Days Ahead and the Ultimate Cataclysm tileset is the result of contributions from volunteers under the Creative Commons Attribution ShareAlike 3.0 license. The code and content of the ...

God promises Abram, at the age of 99, that Sarah shall have a son (17:16,19; 18:10). God's Covenant with Abram embraced circumcision. God changes Abram to Abraham, meaning father of a multitude ...