Ponsegromab increased weight and activity levels in cachexia patients, confirming GDF-15 as a key driver and therapeutic ...

With cachexia, a patient loses a significant amount of weight due to their disease, with considerable losses of muscle mass. Muscle plays essential roles in movement, exercise and metabolism. Simple ...

The study showed that physical fitness matters more than muscle mass. Most patients were debilitated and suffering from some ...

Unfortunately, cachexia, or involuntary weight loss, is a major concern for many individuals with advanced cancer. A new study from Japan has revealed that lower cachexia rates, particularly with ...

Cachexia could be the next blockbuster area ... Current approaches consist of efforts to maximise nutrition, exercise, and rehabilitation. Additional approaches, such as glucocorticoids, may ...

Physical exercise is currently the only recommended ... gene interactions associated with skeletal muscle aging, Journal of Cachexia, Sarcopenia and Muscle (2024). DOI: 10.1002/jcsm.

Could we somehow reverse this process by improving muscle function through exercise, making these cells more resistant to inflammation, breaking the vicious circle of cachexia and muscle loss ...