Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene ...

A protein’s life is anything but simple. Discover how transcription, translation, folding, modification, and degradation work together to preserve proteome integrity.

In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. The finding challenges the dogma ...

Propagation of expression noise from mRNA to protein level is influenced by variation in availability of ribosomal machinery.

With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology advances.

This mini-review synthesises evidence showing that adenosine-to-inosine RNA editing plays an important regulatory role in cardiovascular development, cellular homeostasis, and disease biology. It ...

AI can help protein engineers optimize the transcription enzymes used to make mRNA-based vaccines and therapeutics, say the authors of a new study.

“Too many GPUs makes you lazy,” says the French startup’s vice president of science operations, as the company carves out a different path than the major US AI companies. On Wednesday, the Paris-based ...

Abstract: In the context of a more linked and globalized society, the significance of proficient cross-cultural communication has been increasing to a position of utmost importance. Language functions ...