Pancreatic exocrine insufficiency (PEI) is an under-recognised cause of chronic diarrhoea in patients with neuroendocrine tumours (NETs). If left untreated or undertreated, PEI can lead to ...

Pulse oximetry guides the management of respiratory conditions through non-invasively monitoring arterial oxygen saturation. Unstable haemoglobin variants may produce inaccurate readings. We describe ...

A woman in her 40s presented with progressive cognitive decline, expressive language difficulty and episodic confusion. Her initial symptoms were misattributed to psychiatric illness, and later to ...

A woman in her late 20s presented with a 5-year history of progressive fatigue and generalised weakness. Examination revealed signs of premature ageing, anaemia, neuropathy and hepatosplenomegaly.

Extramedullary haematopoiesis (EMH) is a clinical manifestation of myelofibrosis (MF), which can lead to significant localised symptoms. A patient in her 70s with a history of MF presented with a ...

Coarctation of the aorta (COA) is a relatively common cardiovascular congenital anomaly. It can be seen in up to 6 per 1000 live births. Rare cardiovascular anomalies have been found to be associated ...

A female in her early 30s with a previous history of postpartum granulomatous hypophysitis presented with palpitations and a syncopal episode. She was haemodynamically unstable on arrival with a heart ...

Rosai–Dorfman disease is a rare benign histiocytic proliferative disease of unknown cause that, in exceptional cases, presents with lesions confined to the skin. Clinically variable types of lesions ...

A 6½ years Indian boy was brought by his parents, who were anxious about the excessive increase in the size of the boy's phallus, from the age of 2 years. On physical examination, the child had a ...

Osteoma of the temporal bone is an unusual benign slow-growing tumour composed of mature lamellar bone. It is a single pedunculated mass that often occurs unilaterally. Osteomas of external auditory ...