Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene ...
Pharmaceutical Technology on MSN
RNA-targeting small molecules: a new frontier of drug discovery
With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology advances.
14don MSN
Versatile enzyme that quickly, accurately synthesizes RNA can also perform reverse transcription
From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine. But as their use continues to grow, so does a fundamental challenge: producing RNA ...
Premature termination of transcription influences ribosomal RNA output and RNA polymerase I drug sensitivity, revealing a mechanism of resistance to transcription-targeting chemotherapy.
AZoLifeSciences on MSN
The life cycle of a protein
A protein’s life is anything but simple. Discover how transcription, translation, folding, modification, and degradation work together to preserve proteome integrity.
For the first time, scientists have been able to watch the flu virus live as it infects human airway cells. They developed a ...
AZoLifeSciences on MSN
Cryo-EM uncovers alarmone-driven RNA transcription initiation
Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown molecular mechanism by which the transcription of genetic information from ...
News-Medical.Net on MSN
Study explores how reversible RNA editing could transform future cardiovascular medicine
By Hugo Francisco de Souza Emerging research suggests reversible RNA editing mechanisms may influence heart disease biology while opening new avenues for biomarkers and next-generation cardiovascular ...
Researchers identified how the poxvirus protein VITF-3 forms a molecular ring that clamps onto DNA with viral RNA polymerase, ...
A research team at the University of Würzburg has deciphered another aspect of poxviral gene activation. The study reveals a ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results