Additionally, the Phase 1 clinical trial evaluating QTX3034, an oral G12D-preferring multi-KRAS inhibitor, as a monotherapy and in combination with cetuximab, continues to enroll patients, and data is ...

Trametinib, a mitogen-activated protein kinase (MEK) inhibitor, reduces mortality and morbidity in children with severe ...

Discover Trametinib as a promising treatment for severe hypertrophic cardiomyopathy in children with RASopathies.

OS is an important factor that leads to DNA damage and stimulates carcinogenesis through dysregulation of signaling pathways that are important for tumor survival and metastasis. Studies have ...

Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, United States The MAP2K7 signaling pathway activates the c-Jun NH2 ... Stress signals activate the upstream MAP kinase ...

Explaining further, lead researcher Dr. Takahiro Osada says, "This study used MRI and brain stimulation to map the macroscopic brain circuits responsible for stopping inappropriate actions ...

Explaining further, lead researcher Dr. Takahiro Osada says, "This study used MRI and brain stimulation to map the macroscopic ... revealed a four-step neural pathway involved in response ...

For years, overshadowed by its neighboring emirates of Dubai and Abu Dhabi, Ras Al Khaimah (RAK) is now stepping into the spotlight as one of the UAE’s most promising real estate hotspots for ...