Anti-obesity drug improves metabolism beyond weight loss, study finds

The skin over a mouse’s shoulders warmed up after a dozen days on tirzepatide. That heat map, taken with an infrared camera, pointed to a familiar patch of tissue between the shoulder blades: brown ...
AlphaGalileo

Mitochondria and aging: A central axis in Parkinson’s disease pathogenesis

New review unravels how mitochondrial dysfunction and cellular aging converge to drive Parkinson’s disease Parkinson’s disease (PD) is a progressive ...
Medical Xpress

Molecular Function: Oxidative Phosphorylation

In a bid to better understand how cancer cells power their explosive growth and spread, scientists at Johns Hopkins Medicine say they have shed new light on the location and function of ...
ksn.com

Aetheion® Introduces Science-Driven Solution to Help Counter Skin-Level Oxidative Stress

A woman enjoying skincare benefits—Aetheion® promotes healthy, radiant skin through antioxidant support. Aetheion® introduces a science-backed skincare solution designed to help combat oxidative ...
ascopubs.org

Clear and non-clear cell renal cell carcinomas and the ability to engage in oxidative phosphorylation.

Neoadjuvant lenvatinib plus pembrolizumab for resectable clear-cell renal cell carcinoma (PELUR): A prospective phase 2 study. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I.
Scientific Research Publishing

Nolfi-Donegan, D., Braganza, A. and Shiva, S. (2020) Mitochondrial Electron Transport Chain: Oxidative Phosphorylation, Oxidant Production, and Methods of Measurement. Redox ...

ABSTRACT: This study aimed to optimize process variables for the enhanced production of single-cell protein (SCP) using Trichoderma atroviride EGER23 from cassava peels through Response Surface ...
Frontiers

Regulating mitochondrial oxidative phosphorylation and MAPK signaling: wedelolactone as a novel therapeutic for radiation-induced thrombocytopenia

In vitro experiments were conducted using Meg‐01 and K562 cell lines to evaluate the effects of WED on megakaryocyte differentiation and maturation. Flow cytometry and phalloidin staining were ...
C&EN

Bringing Histidine Phosphorylation into Light: Role of Chemical Tools

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...
Cancer Research

Oxidative Phosphorylation Is a Metabolic Vulnerability of Endocrine Therapy–Tolerant Persister Cells in ER + Breast Cancer

1Department of Molecular and Systems Biology, Dartmouth Geisel School of Medicine, Lebanon, New Hampshire.
EurekAlert!

ING5 inhibits aerobic glycolysis of lung cancer cells by promoting TIE1-mediated phosphorylation of pyruvate dehydrogenase kinase 1 at Y163

Lung cancer, notorious for its high mortality rates, is a leading cause of cancer-related deaths globally, with metastasis being the primary contributor to poor patient outcomes. A critical factor in ...
News Medical

ING5 regulates metabolic reprogramming in lung cancer cells

Lung cancer, notorious for its high mortality rates, is a leading cause of cancer-related deaths globally, with metastasis being the primary contributor to poor patient outcomes. A critical factor in ...