Once activated, Ras can do a variety of things. In this example, it activates an enzymatic cascade of MAP kinases ... activates an enzyme called a kinase. Learn how kinases initiate a signaling ...

In contrast, the signal proceeds normally or with greater strength (because of compensatory hyperinsulinemia of various degrees) along the Shc-Ras-MAP kinase pathway, eliciting greater responses ...

Using this technique, they were able to identify known and novel protein interactions linking the epidermal growth factor receptor with the Ras/MAP kinase signaling pathway (see p. 1193).

found in up to 85% of cancers driven by RAS alterations. Developed in-house, BAY3498264 addresses the unmet medical need of improving efficacy of treatment targeting the mitogen-activated protein ...