For example, Ras proteins function as molecular switches ... function of proto-oncogenes and oncogenes that drive the cell cycle forward, tumor suppressor genes code for proteins that normally ...

We now know that, depending on the cellular context, Ras can contribute to cell-cycle arrest and cell differentiation, or to the tissue-specific functions of cells that no longer divide or ...

Decades of research have shown that mutant RAS proteins promote the development and growth of tumors by activating specific proteins at the cell surface, creating a constant stream of signals ...