Diabetic nephropathy (DN), characterized by progressive damage to the glomeruli and tubulointerstitial compartments, is driven by metabolic reprogramming and mitochondrial dysfunction, including ...

They fall into the following main categories: mitochondria-targeted antioxidants, modulating mitochondrial dynamics, enhancing mitochondrial quality control, potentiating mitochondrial biogenesis, ...

The central goal of research in the Mears Lab is to investigate proteins that regulate mitochondrial dynamics. Mitochondrial dynamics has recently come to the forefront as a therapeutic target in ...

Many of us remember from high school biology class that mitochondria are the cell’s “power plants.” These small kidney-bean-shaped structures are what convert nutrients from food into ATP — the cell’s ...

Mitochondria are the cell's power plants: They turn the food we eat into the energy our cells can use. But when stress hijacks the process they use to maintain their quality, they get snipped into ...

Some brain disorders are straightforward, such as the direct frontal lobe assault of a concussion or traumatic brain injury. Others, like Alexander disease, are akin to guerilla warfare. Patients ...