In 1997, Alan Leshner, then director of the National Institute for Drug Abuse, wrote an article entitled “Addiction Is a Brain Disease and It Matters.” That eight-word title became the perfect sound ...

Is addiction a disease? Do the kids I work with at CASTLE have a pathological response to drugs and alcohol? The disease model of addiction is compelling, and has served its purpose in bringing needed ...

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Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse disorder ...

New research shows chronic alcohol use rewires gene activity in human brain regions that control reward and decision-making, ...

Alcohol does not simply relax the mind. It rewires it. With repeated use, drinking can splinter the brain’s carefully ...

Scientists have recreated morphine-like pain relief in mice with a targeted therapy that avoids addiction-linked brain ...

Excessive use of screens affects sleep and attention span and contributes to anxiety, depression, and a reduction in real-world social interactions ...

Addiction has causes that are neurobiological, psychological and structural. Treating these drivers is as important as managing the initial withdrawal. Medically managed withdrawal does not restore ...