This season, the injury-riddled San Francisco 49ers have been forced to rely on a litany of unlikely heroes. First there was running back Jordan Mason, who ably filled in for injured superstar Christian McCaffrey the first month of the season. Then ...

Guerendo had a chance to score a touchdown on Thursday, but chose to slide down short in order to preserve a 49ers win

San Francisco 49ers running back Isaac Guerendo doesn't want the latest edition of the Madden video game to alter his speed. Guerendo had a 76-yard run to start the 49ers' game-winning drive and could've scored but decided to go down inside the five-yard line.

Welcome to the Friday edition of the Pick Six newsletter! I hope everyone remembers to set their alarms for Sunday morning, because we have another early international game this week with the Bears playing the Jaguars in London at 9:30 a.

San Francisco 49ers withstood a Seattle Seahawks comeback as they beat their NFC West rivals 36-24. The 49ers opened a 20-point gap early in the second half, only for the Seahawks to twice bring the game back within a score.

After already blowing 10-point, fourth-quarter leads in embarrassing losses to the Los Angeles Rams and the Arizona Cardinals, the 49ers found themselves Thursday night with a luxurious, 20-point cushion against their other NFC West rival,

Combine the top 49ers-Seahawks betting promos to claim up to $6,000 in bonus bets for Week 6's Thursday Night Football opener.

The top sportsbook promos are offer more than $4K in bonuses for 49ers vs. Seahawks on Thursday Night Football.