Hampton Roads is a body of water in the United States that serves as a wide channel for the James, Nansemond, and Elizabeth rivers between Old Point Comfort and Sewell's Point near where the Chesapeake Bay flows into the Atlantic Ocean. It also gave its name to the surrounding metropolitan region located in the southeastern Virginia and northeas…Hampton Roads is a body of water in the United States that serves as a wide channel for the James, Nansemond, and Elizabeth rivers between Old Point Comfort and Sewell's Point near where the Chesapeake Bay flows into the Atlantic Ocean. It also gave its name to the surrounding metropolitan region located in the southeastern Virginia and northeastern North Carolina portions of the Tidewater Region.