Wooster is the county seat of Wayne County, Ohio, United States. Located in northeastern Ohio, the city lies approximately 50 mi south-southwe…Wooster is the county seat of Wayne County, Ohio, United States. Located in northeastern Ohio, the city lies approximately 50 mi south-southwest of Cleveland, 35 mi southwest of Akron and 30 mi west of Canton. The population was 27,232 at the 2020 census. It is the largest in Wayne County, and the center of the Wooster micropolitan area. Wooster has the main branch and administrative offices of the Wayne County Public Library, and is home to the private College of Wooster. fDi magazine ranked Wooster among North America's top 10 micro cities for business friendliness and strategy in 2013.