Uptown Charlotte, also called Center City, is the central business district of Charlotte, North Carolina, United States. The area is split into four wards by the intersection of Trade and Tryon Streets, and bordered by Interstate 277 and Interstate 77. The area is managed and overseen by the Charlotte Central City Partners, which is one of the three Municipal Service Dis…Uptown Charlotte, also called Center City, is the central business district of Charlotte, North Carolina, United States. The area is split into four wards by the intersection of Trade and Tryon Streets, and bordered by Interstate 277 and Interstate 77. The area is managed and overseen by the Charlotte Central City Partners, which is one of the three Municipal Service Districts in Charlotte. Uptown Charlotte is the largest business district in Charlotte and the Carolinas.