Animal Models for Influenza Research: Strengths and Weaknesses
WEBMay 28, 2021 · Herein, we reviewed the advantages and limitations of each animal model—including mice, ferrets, guinea pigs, swine, felines, canines, and non-human primates—for elucidating influenza viral pathogenesis and transmission and for evaluating therapeutic agents and vaccine efficacy.
Predictive evolutionary modelling for influenza virus by site-based ...
WEBMar 21, 2024 · We develop a computational approach, beth-1, to forecast virus evolution and select representative virus for influenza vaccine. The method involves modelling site-wise mutation fitness.
Types of Influenza Viruses | CDC
WEBMar 30, 2023 · This graphic shows the two types of influenza viruses (A and B) that cause most human illness and that are responsible for flu seasons each year. Influenza A viruses are further classified into subtypes, while influenza B viruses are further classified into two lineages: B/Yamagata and B/Victoria.
Structure and Hierarchy of Influenza Virus Models Revealed by
WEBMay 16, 2019 · Here, we present a new approach to understanding the overall structure of twelve influenza A virus infection models and their relationship to each other. To this end, we apply chemical organization theory to obtain a hierarchical decomposition of the models into chemical organizations.
Computer Model of Influenza Virus Shows Universal Vaccine …
WEBJan 25, 2023 · For the first time, researchers at UC San Diego have created an atomic-level computer model of the H1N1 virus that reveals new vulnerabilities, suggesting possible strategies for the design of future vaccines and antivirals against influenza.
Scientists create accurate predictor of the next flu virus
WEBFeb 28, 2014 · New flu model helps predict future strains. April Mo, CC BY-SA. Influenza viruses rapidly evolve in shape, making it hard to develop protective vaccines against them. Despite a great deal of...
Models for predicting the evolution of influenza to inform vaccine ...
WEBFeb 12, 2018 · We review some of the most recent studies in the literature that propose methods to inform strain selection for the seasonal influenza vaccine. He and Deem 25 constructed protein distance maps for the HA1 surface glycoprotein of the influenza 2009 A (H1N1) pdm virus.
Computer model of influenza virus shows universal vaccine promise
WEBFeb 27, 2023 · For the first time, U.S. National Science Foundation-supported researchers at the University of California San Diego have created an atomic-level computer model of the H1N1 virus that reveals new vulnerabilities …
Computer model of influenza virus shows universal vaccine promise
WEBJan 25, 2023 · For the first time, researchers at the University of California San Diego have created an atomic-level computer model of the H1N1 virus that reveals new vulnerabilities through glycoprotein...
50-year-old flu virus model revamped, revealing pandemic …
WEBJul 13, 2017 · The scientific textbook depiction of the flu virus is about to get a facelift, due to a new discovery that a model of the influenza genome architecture untouched since the 1970s isn't so...