Cancer drug could treat early-stage Alzheimer’s disease, study …
WEBAug 22, 2024 · Cancer drug could treat early-stage Alzheimer’s disease, study shows. Researchers discovered that by blocking a specific enzyme called indoleamine-2,3-dioxygenase 1, or IDO1 for short, they could rescue memory and brain function in models that mimic Alzheimer’s disease.
From Cancer to Brain Health: A New Alzheimer’s Treatment …
WEBSep 1, 2024 · IDO1 inhibitors, drugs originally aimed at cancer, show potential in treating Alzheimer’s by improving brain metabolism. This could lead to therapies that not only manage but potentially reverse aspects of neurodegenerative diseases.
Cell Engineering Team Links Cancer Drug to Potential Therapy for ...
WEBFeb 22, 2024 · In experiments with lab-grown brain cells and mouse models, scientists at Johns Hopkins Medicine say they have discovered that a cell surface protein called Lag3 is not only a biological target for FDA-approved drugs that stimulate the immune system to attack cancer, but also may be a target for a drug designed to clean up “misfolded” Tau ...
Experimental Cancer Drug Developed at MSK Leads to New …
WEBMar 1, 2018 · PU-H71 is now in a phase I/II trial for people with metastatic breast cancer. Based on their discoveries about PU-H71, she and her team later developed a related drug, which they called PU-AD, for Alzheimer’s disease. The fact that there is a common mechanism raises the possibility of a common therapy.
A new drug may help treat early-stage Alzheimer’s by targeting …
WEBSep 4, 2024 · Researchers have identified an enzyme that regulates glucose metabolism in the brain and discovered that a cancer drug may help treat early-stage Alzheimer’s. Treatment with the...
Cancer drug could treat early-stage Alzheimer’s disease, study …
WEBAug 23, 2024 · The researchers discovered that by blocking a specific enzyme called indoleamine-2,3-dioxygenase 1, or IDO1 for short, they could rescue memory and brain function in models that mimic Alzheimer’s disease.
Repurposed cancer treatments could be potential Alzheimer’s drugs
WEBNov 10, 2021 · Existing and emerging cancer drugs could be repurposed as therapies to be tested in clinical trials for people at genetic risk of Alzheimer’s disease, according to a new study published in Science Advances.
Cancer drug could treat early-stage Alzheimer - EurekAlert!
WEBAug 22, 2024 · Researchers discovered that by blocking a specific enzyme called indoleamine-2,3-dioxygenase 1, or IDO1 for short, they could rescue memory and brain function in models that mimic...
Anticancer drugs repurposed for Alzheimer’s disease: a …
WEBMay 5, 2021 · The relationship between cancer and dementia is triggering growing research interest. Several preclinical studies have provided the biological rationale for the repurposing of specific anticancer agents in Alzheimer’s disease (AD), and a growing number of research protocols are testing their efficacy and safety/tolerability in patients …
Repurposed experimental cancer drug restores brain function …
WEBScientists have found that a compound originally developed as a cancer therapy potentially could be used to treat Alzheimer’s disease. The team demonstrated that the drug, saracatinib, restores memory loss and reverses brain problems in mouse models of Alzheimer’s, and now the researchers are testing saracatinib’s effectiveness in humans.